Education

Ph.D.  Biostatistics, University of South Carolina, 2013

Background

Chao Cai, Ph.D. is an assistant professor in the Department of Clinical Pharmacy and Outcomes Sciences at the University of South Carolina College of Pharmacy in Columbia, South Carolina.

Dr. Cai received her masters degree in Applied Statistics from University of Pittsburgh in 2003 and Ph.D. in Biostatistics from the University of South Carolina in 2013. Her areas of expertise include applying advanced statistical methods in outcomes sciences and providing statistical consulting in collaborative research.

Research Interests

• Latent Variable Analysis
• Survival Analysis
• Mediation Analysis
• Medication Adherence Research
• Schizophrenia, Alzheimer Disease and Related Dementia (ADRD)
• AI in Outcomes Research

Awards & Honors

• Emerging Researcher Award, USC College of Pharmacy, 2026

Publications

Cai C, Zhao P, Patel C, Benson C, Yunusa I, Kozma C, Reeder G. Latent variable analysis of adherence to antipsychotics among South Carolina Medicaid beneficiaries with schizophrenia or schizoaffective disorder. Psychiatry Research. 2025 Feb 10;346:116402. PMID: 39983530; PMCID: PMC11252894. https://doi.org/10.1016/j.psychres.2025.116402

Cai C, Strickland K, Knudsen S, Tucker SB, Chidrala CS, Modugno F. Alzheimer Disease and Related Dementia Following Hormone-Modulating Therapy in Patients with Breast Cancer. JAMA Network Open. 2024 Jul 1;7(7):e2422493.  PMID: 39012631; PMCID: PMC11252894. https://doi.org/10.1001/jamanetworkopen.2024.22493

Cai C, Kozma C, Patel C, Benson C, Yunusa I, Zhao P, Reeder G, Narasimhan M, Bank RL. Adherence, health care utilization, and costs between long-acting injectable and oral antipsychotic medications in South Carolina Medicaid beneficiaries with schizophrenia. Journal of Managed Care and Specialty Pharmacy. 2024 Jun;30(6):549-559.  PMID: 38824623; PMCID: PMC11144998. https://doi.org/10.18553/jmcp.2024.30.6.549

Cai C, Love BL, Yunusa I, Reeder CE. Applying mixture cure survival modeling to medication persistence analysis. Pharmacoepidemiology and Drug Safety. 2022;1‐8.PMID: 35426193. https://doi.org/10.1002/pds.5441

Cai C, Yunusa I, Tarhini A. Estimated Cost-effectiveness of Atezolizumab Plus Cobimetinib and Vemurafenib for Treatment of BRAF V600 Variation Metastatic Melanoma. JAMA Network Open. 2021 Nov 1;4(11):e2132262. PMID: 34762112; PMCID: PMC8586909.https://doi.org/10.1001/jamanetworkopen.2021.32262

Wang Y, Zhang J, Cai C, Lu W, Tang Y. Semiparametric estimation for proportional hazards mixture cure model allowing non-curable competing risk. Journal of Statistical Planning and Inference. 2021;211:171–189. doi:10.1016/j.jspi.2020.06.009

Fairchild A, Cai C, McDaniel H, Shi D, Gottschall A, Masyn K, Evaluating A method to Estimate Mediation Effects with Discrete-Time Survival Outcomes. Frontiers in Psychology, Quantitative Psychology and Measurement, 2019;10:740. PMID: 31024391; PMCID: PMC6460901.https://doi.org/10.3389/fpsyg.2019.00740

Cai C, Wang S, Lu W, Zhang J, NPHMC: An R-Package for estimating sample size of proportional hazards mixture cure models, Computer Methods and Programs in Biomedicine, 113: 290-300, 2014. PMID: 24199658; PMCID: PMC3859312.https://doi.org/10.1016/j.cmpb.2013.10.001

Cai C, Zou Y, Peng Y, Zhang J, smcure: An R-Package for estimating semiparametric mixture cure models, Computer Methods and Programs in Biomedicine, 108:1255–1260, 2012. PMID: 23017250; PMCID: PMC3494798. https://doi.org/10.1016/j.cmpb.2012.08.013

See more: 
NCBI Bibliography  |  Google Scholar Profile

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