The Institute's Research Goals
Research Terminology:
Understand how inflammasome activation participates in the pathogenesis of neurogenic
hypertension due to chronic unpredictable stress.
Research Terminology:
Evaluate the role of sex differences in inflammasome activation in relation to neurogenic
hypertension.
Research Terminology:
Initiate an understanding of possible therapeutic approaches targeting NLRP3 and AIM2
inflammasomes.
Year-by-Year Goals and Outcomes
The Institute for Cardiovascular Disease Research has outlined the following yearly research goals for the first four years of the institute's trajectory.
Demonstrate activation of the NLRP3/profibrotic pathway, including measurements of TGF activation, collagen expression and content
Establish final osmotic pump delivery protocols
Continue the themes of years one and two with goals to be detailed as research progresses
Continue the themes of years one and two with goals to be detailed as research progresses